The CLEO-c experimental program for charm physics is described. This talk will focus on the weak decays of D and Ds mesons. Recent results on 281 pb-1 of data taken at the psi(3770) for studies of D mesons, including the absolute hadronic branching fractions, semileptonic and leptonic decays, are discussed. CLEO-c has also analyzed about 200 pb-1 of data recorded at E_cm=4170 MeV. At this energy we produce DsDs* pairs and study decays of the Ds mesons.