Abstract: Fermilab operates the world's most intense antiproton source. With the Tevatron Collider program over, recently proposed experiments can use those antiprotons for unique and important measurements. For example, the annihilation of 5 to 8 GeV antiprotons is expected to yield world-leading sensitivities to hyperon rare decays and CP violation. It could also provide the world's most intense source of tagged D^0 mesons, and thus the best near-term opportunity to study charm mixing and, via CP violation, to search for new physics. Other measurements that could be made include the antiproton Drell-Yan continuum and properties of the X(3872) and the charmonium system. An experiment using a Penning trap and an atom interferometer could make the world's first measurement of the gravitational force on antimatter. The experiments are sufficiently cost-effective to be practical even in the tight-budget scenarios that are upon us. These and other potential measurements using antiprotons offer a great opportunity for a broad and exciting physics program at Fermilab in the post-Tevatron era.